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10 bestSinus Decongestantsof December 2025

112M consumers helped this year.

1

Vicks VapoRub Nasal Decongestant, Cough Suppressant, Relief from Cold, Aches, & Pains, Chest Rub Ointment, Original Scent, 100 g/115 mL
Vicks VapoRub Nasal Decongestant, Cough Suppressant, Relief from Cold, Aches, & Pains, Chest Rub Ointment, Original Scent, 100 g/115 mL

Vicks

10.0

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16% off

2

TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Daytime and Nighttime, Convenience Pack, 40ct
TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Daytime and Nighttime, Convenience Pack, 40ct

Tylenol

10.0

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3

HydraSense NetiRinse 2-in-1 Nasal and Sinus Irrigation Kit, Helps Reduce and Relieve Nasal and Sinus Symptoms, 60 Count (Pack of 1)
HydraSense NetiRinse 2-in-1 Nasal and Sinus Irrigation Kit, Helps Reduce and Relieve Nasal and Sinus Symptoms, 60 Count (Pack of 1)

HydraSense

9.7

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4

Xlear Nasal Spray, Natural Saline Nasal Spray with Xylitol, Nose Moisturizer for Kids and Adults, 45 ml (Pack of 1)
Xlear Nasal Spray, Natural Saline Nasal Spray with Xylitol, Nose Moisturizer for Kids and Adults, 45 ml (Pack of 1)

Xlear

9.5

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5

NEOCITRAN® ES Cold & Sinus Night Lemon
NEOCITRAN® ES Cold & Sinus Night Lemon

ZEP-PRO

9.3

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Related productsUp to 31% off

TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Nighttime, 40ct

TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Nighttime, 40ct

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OTRIVIN Medicated Complete Nasal Care (Spray) (Measured Dose Mist)

OTRIVIN Medicated Complete Nasal Care (Spray) (Measured Dose Mist)

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Vicks DayQuil COMPLETE Cold and Flu LiquiCaps Medicine, Non-Drowsy Daytime Multi-Symptom Relief for Cough , Congestion, Fever, Sore Throat Pain, 24 Count

Vicks DayQuil COMPLETE Cold and Flu LiquiCaps Medicine, Non-Drowsy Daytime Multi-Symptom Relief for Cough , Congestion, Fever, Sore Throat Pain, 24 Count

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Mucinex Multi-Action Congestion, Cold, & Cough Caplets, 20 count

Mucinex Multi-Action Congestion, Cold, & Cough Caplets, 20 count

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6

Nasol Capsaicin Nose Spray Decongestant Nasal Spray 1oz/30 ml - Natural Allergy Nose Spray For Stuffy Nose, Natural Sinus Spray, Nasal Decongestant Spray Providing Relief From Sinus Pressure, Headaches, Nasal and Sinus Congestion (4)
Nasol Capsaicin Nose Spray Decongestant Nasal Spray 1oz/30 ml - Natural Allergy Nose Spray For Stuffy Nose, Natural Sinus Spray, Nasal Decongestant Spray Providing Relief From Sinus Pressure, Headaches, Nasal and Sinus Congestion (4)

Nasol

9.0

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10% off

7

BENYLIN Extra Strength Cough and Chest Congestion Syrup, Suitable for People with Diabetes, Sucrose Free, Relieves Cough and Nasal Congestion, 100mL
BENYLIN Extra Strength Cough and Chest Congestion Syrup, Suitable for People with Diabetes, Sucrose Free, Relieves Cough and Nasal Congestion, 100mL

BENYLIN

8.8

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38% off

8

Mucinex Chest Congestion Guaifenesin 600 mg Tablets Expectorant (Cough Medicine), 20 Count
Mucinex Chest Congestion Guaifenesin 600 mg Tablets Expectorant (Cough Medicine), 20 Count

Mucinex

8.5

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9

Drixoral Nasal Congestion Spray, Soothes and Moisturizes Dry and Irritated Nasal Passages, 25ml
Drixoral Nasal Congestion Spray, Soothes and Moisturizes Dry and Irritated Nasal Passages, 25ml

Drixoral

8.2

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10

TYLENOL Sinus Extra Strength eZ Tabs, Relieves Sinus congestion and other Sinus symptoms, Daytime and Nighttime, Convenience Pack, 40ct
TYLENOL Sinus Extra Strength eZ Tabs, Relieves Sinus congestion and other Sinus symptoms, Daytime and Nighttime, Convenience Pack, 40ct

Tylenol

8.0

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