10 bestPeriod Pain Killerof December 2025
112M consumers helped this year.
16% off
1
Tylenol Extra Strength For Pain Relief, Headache Relief, and Reducing Fever, 500 mg Acetaminophen 150 eZTABS
Tylenol
9.8
2
Advil Regular Strength Ibuprofen Pain Relief Liquid-Gels, Fast Acting Pain Relief for Migraine, Back, Neck, Joint, and Muscle Relief, 200mg (72 Count)
Advil
9.6
3
Livia-The Off Switch for Menstrual Pain. Instant Treatment for Period Cramps. Natural Drug-Free, Medical Device for PMS Relief with 3 Months Supply of Livia Gel Pads, Blue-Green
Livia
9.3
4
Motrin Super Strength Tablets, Pain Reliever for Menstrual Pain, Headaches, Back Pain, Ibuprofen 400mg, 45 Tablets
Motrin
9.1
5
Advil Regular Strength Ibuprofen Pain Relief Mini-Gels Capsules, Fast Acting Pain Relief for Migraine, Back, Neck, Joint, and Muscle Relief, 200mg (70 capsules)
Advil
8.8
Other
ALEVE Pain relief liquid Gels, Strength To Last Up To 12 hours, Naproxen Sodium 220mg 30 count
CanPrev Cramp Relief | 120 v-caps | Relieves Muscle Spasms, & Pain Associated With Menstruation | Relieves Nervousness And Tension Associated With Painful Periods
(5 Patches) CrampCareH PMS/Menstrual Cramps Relief Heat Patch with Wide Wings, FDA Registered
Combogesic - Double Action Acetaminophen + Ibuprofen Tablets for Acute Pain and Fever Relief - Headache and Acute Migraine Relief, Menstrual Pain Relief, Muscle Aches, Dental Pain Relief - 30 Tablets
9% off
6
ALEVE Back and Body Pain Relief, clinically proven, Fast-Acting, Long-lasting, Naproxen Sodium 30 count
Aleve
8.5
7
Kalaya Extra Strength Pain Relief Cream With Cannabis Sativa Seed Oil (60g Pack of 1) - Natural Active, Pain Blocking & Anti inflammatory Ingredients Suitable for Arthritis, Neck, Shoulder, Hand, Knee, Back, Joint & Muscle Pain
Kalaya
8.2
8
Advil Extra Strength Ibuprofen Pain Relief Caplets, Fast Acting Pain Relief for Migraine, Back, Neck, Joint, and Muscle Relief, 400mg (32 Count)
Advil
7.9
27% off
9
Advil Muscle and Joint (32 Count) 400 mg ibuprofen, Muscle Pain, Joint Pain, Temporary Pain Reliever
Advil
7.6
10
Advil Tablets (50 Count), 200 mg ibuprofen, Temporary Pain Reliever / Fever Reducer
Advil
7.3
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