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10 bestPain Medicationsof November 2025

112M consumers helped this year.

16% off

1

Tylenol Extra Strength For Pain Relief, Headache Relief, and Reducing Fever, 500 mg Acetaminophen 150 eZTABS

Tylenol Extra Strength For Pain Relief, Headache Relief, and Reducing Fever, 500 mg Acetaminophen 150 eZTABS

Tylenol Extra Strength For Pain Relief, Headache Relief, and Reducing Fever, 500 mg Acetaminophen 150 eZTABS

Tylenol

9.8

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2

Advil Regular Strength Ibuprofen Pain Relief Liquid-Gels, Fast Acting Pain Relief for Migraine, Back, Neck, Joint, and Muscle Relief, 200mg (72 Count)

Advil Regular Strength Ibuprofen Pain Relief Liquid-Gels, Fast Acting Pain Relief for Migraine, Back, Neck, Joint, and Muscle Relief, 200mg (72 Count)

Advil Regular Strength Ibuprofen Pain Relief Liquid-Gels, Fast Acting Pain Relief for Migraine, Back, Neck, Joint, and Muscle Relief, 200mg (72 Count)

Advil

9.6

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10% off

3

VOLTAREN Emulgel Extra Strength (Gel), topical pain gel, 100g

VOLTAREN Emulgel Extra Strength (Gel), topical pain gel, 100g

VOLTAREN Emulgel Extra Strength (Gel), topical pain gel, 100g

Voltaren

9.4

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4

Genacol Collagen Supplement | Helps Relieve Joint Pain | Knee Pain and Back Pain Relief | Ultra-Hydrolyzed Peptides for Increased Bioavailability | GENACOL ORIGINAL 150 Capsules

Genacol Collagen Supplement | Helps Relieve Joint Pain | Knee Pain and Back Pain Relief | Ultra-Hydrolyzed Peptides for Increased Bioavailability | GENACOL ORIGINAL 150 Capsules

Genacol Collagen Supplement | Helps Relieve Joint Pain | Knee Pain and Back Pain Relief | Ultra-Hydrolyzed Peptides for Increased Bioavailability | GENACOL ORIGINAL 150 Capsules

Genacol

9.2

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5

KaLaya 6X Extra Strength Pain Relief Cream for Arthritis, Joints, Muscle, Back, Neck, Shoulder, Hand and Knee Pain - Medically formulated with 6 Natural Active, Pain Blocking & Anti inflammatory Ingredients (120g)

KaLaya 6X Extra Strength Pain Relief Cream for Arthritis, Joints, Muscle, Back, Neck, Shoulder, Hand and Knee Pain - Medically formulated with 6 Natural Active, Pain Blocking & Anti inflammatory Ingredients (120g)

KaLaya 6X Extra Strength Pain Relief Cream for Arthritis, Joints, Muscle, Back, Neck, Shoulder, Hand and Knee Pain - Medically formulated with 6 Natural Active, Pain Blocking & Anti inflammatory Ingredients (120g)

Kalaya

8.9

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OtherRelated productsUp to 22% off

• Tylenol Extra Strength For Pain Relief, Headache Relief, and Reducing Fever, 500 mg Acetaminophen 150 Caplets

• Tylenol Extra Strength For Pain Relief, Headache Relief, and Reducing Fever, 500 mg Acetaminophen 150 Caplets

Tylenol Children's Chewables Fever and Pain Relief, Bubble Gum Flavour, 160 mg Acetaminophen, 20 Tablets, Toothache Pain Relief

Tylenol Children's Chewables Fever and Pain Relief, Bubble Gum Flavour, 160 mg Acetaminophen, 20 Tablets, Toothache Pain Relief

ALEVE Back and Body Pain Relief, clinically proven, Fast-Acting, Long-lasting, Naproxen Sodium 30 count

ALEVE Back and Body Pain Relief, clinically proven, Fast-Acting, Long-lasting, Naproxen Sodium 30 count

Stanley Pharmaceuticals Arthritis Pain Relief Tablets USP 650 Mg 100 count(packaging might vary)

Stanley Pharmaceuticals Arthritis Pain Relief Tablets USP 650 Mg 100 count(packaging might vary)

6

MEDISTIK Extra Strength Pain Relief Stick. Long Lasting Topical Pain Reliever for Backache, Arthritis, Knee, Muscle & Joint Pain (1)

MEDISTIK Extra Strength Pain Relief Stick. Long Lasting Topical Pain Reliever for Backache, Arthritis, Knee, Muscle & Joint Pain (1)

MEDISTIK Extra Strength Pain Relief Stick. Long Lasting Topical Pain Reliever for Backache, Arthritis, Knee, Muscle & Joint Pain (1)

Medistik

8.7

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7

Motrin Super Strength Tablets, Pain Reliever for Menstrual Pain, Headaches, Back Pain, Ibuprofen 400mg, 45 Tablets

Motrin Super Strength Tablets, Pain Reliever for Menstrual Pain, Headaches, Back Pain, Ibuprofen 400mg, 45 Tablets

Motrin Super Strength Tablets, Pain Reliever for Menstrual Pain, Headaches, Back Pain, Ibuprofen 400mg, 45 Tablets

Motrin

8.4

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8

Tylenol Arthritis Pain, Acetaminophen 650 mg Caplets, Fast & Long Lasting Arthritis, Muscle & Joint Pain Relief, 50 Caplets

Tylenol Arthritis Pain, Acetaminophen 650 mg Caplets, Fast & Long Lasting Arthritis, Muscle & Joint Pain Relief, 50 Caplets

Tylenol Arthritis Pain, Acetaminophen 650 mg Caplets, Fast & Long Lasting Arthritis, Muscle & Joint Pain Relief, 50 Caplets

Tylenol

8.1

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9

Advil Arthritis Pain (45 Count) 400 mg ibuprofen, Inflammation and Temporary Pain Reliever

Advil Arthritis Pain (45 Count) 400 mg ibuprofen, Inflammation and Temporary Pain Reliever

Advil Arthritis Pain (45 Count) 400 mg ibuprofen, Inflammation and Temporary Pain Reliever

Advil

7.8

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10

Tylenol Extra Strength 500 mg eZ Tab, Pack of 2 (300tab Total)

Tylenol Extra Strength 500 mg eZ Tab, Pack of 2 (300tab Total)

Tylenol Extra Strength 500 mg eZ Tab, Pack of 2 (300tab Total)

Tylenol

7.6

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