10 bestOver The Counter Acne Spot Treatmentof November 2025
112M consumers helped this year.
1
Rael Miracle Invisible Spot Cover - Absorbing Cover, Skin Care, Facial Stickers, 2 Sizes (96 Count)
Rael
9.7
5% off
2
CeraVe 4% Benzoyl Peroxide ACNE Treatment Foaming Cleanser Face & Body Wash, with Hyaluronic Acid and Niacinamide. Helps Clear Acne Pimples and prevent breakouts. Gentle Gel, Fragrance-Free, 150ML
CeraVe
9.4
3
PanOxyl Creamy Acne Wash - 4% Benzoyl Peroxide
Panoxyl
9.1
4
Proactiv Repair Acne Treatment - Benzoyl Peroxide Spot Treatment And Repairing Serum - 60 Day Supply, 3oz.
Proactiv
8.8
30% off
5
CeraVe Acne Control Gel For Face, Pimple & Pores, With Salicylic Acid, 3 Essential Ceramides, Niacinamides. Developed with Dermatologists, Non-Comedogenic, Oil-Free, Fragrance-Free, 40ml
CeraVe
8.5
OtherUp to 30% off
Cetaphil Gentle Salicylic Acid Acne Serum| For Sensitive, Acne Prone Skin | With Salicylic Acid, Niacinamide, Zinc, Prebiotics | Triple Action Formula Treats, Prevents and Reduces Acne | Fragrance Free | Hypoallergenic | Dermatologist Recommended
Oxy Deep Pore Cleansing Acne Pads - Salicylic Acid 2.0% – Stubborn Acne Control - Helps Treat, and Prevent Breakouts – Paraben & Preservative Free - Dermatologist Tested
Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel with Maximum Strength 5% Benzoyl Peroxide Acne Treatment Medication for Acne Prone Skin Care, 28g
Vichy Normaderm Anti-Acne Spot Treatment With 10% Sulfur, Glycolic Acid & Niacinamide Vitamin B3. Dries out pimples overnight, prevents acne blemishes. Fragrance-free, Dermatologists-recommended, 20ML
6
Rael Miracle Spot Control Cover - Large Size, Long and Extra Coverage, Hydrocolloid Strip (20 Count)
Rael
8.2
7
Proactiv+ Benzoyl Peroxide Acne Treatment - Pore Targeting Acne Spot Treatment - 90 Day Supply, 89 ml
Proactiv
7.9
8
Vivier Acne Treatment System
Vivierskin
7.6
12% off
9
PanOxyl Clarifying Exfoliant, with 2% Salicylic Acid, Leave-On Treatment, Helps Clear and Prevent Acne Pimples, Penetrates Pores for Clearer Skin, pH-balanced, Alcohol-Free Formula, 118ml
Panoxyl
7.3
10
Clean & Clear Persa-Gel 5 Oil-Free Acne Spot Treatment with Maximum Strength 5% Benzoyl Peroxide, Topical Pimple & Acne Medication for Face Acne, Fragrance-Free, 28g
Clean & Clear
7.0
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