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10 bestOtc Sinus Medicinesof June 2025

112M consumers helped this year.

1

Reactine Extra Strength Antihistamine Tablets - 10mg Cetirizine Hydrochloride - 24 Hour Allergy Relief Medicine - 10 Count
Reactine Extra Strength Antihistamine Tablets - 10mg Cetirizine Hydrochloride - 24 Hour Allergy Relief Medicine - 10 Count

Reactine

9.8

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2

Drixoral Nasal Congestion Spray, Soothes and Moisturizes Dry and Irritated Nasal Passages, 25ml
Drixoral Nasal Congestion Spray, Soothes and Moisturizes Dry and Irritated Nasal Passages, 25ml

Drixoral

9.6

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3

Flonase Allergy Relief Nasal Spray 120 Sprays
Flonase Allergy Relief Nasal Spray 120 Sprays

Flonase

9.3

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4

Neocitran Extra Strength Cold & Sinus Apple Cinnamon
Neocitran Extra Strength Cold & Sinus Apple Cinnamon

ZEP-PRO

9.0

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5

Stanley 24 hour Allergy Remedy, 20 Tablets, Fast relief from seasonal allergy symptoms
Stanley 24 hour Allergy Remedy, 20 Tablets, Fast relief from seasonal allergy symptoms

Stanley

8.8

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Related productsUp to 20% off

Dristan Long Lasting Nasal Mist (30 mL)

Dristan Long Lasting Nasal Mist (30 mL)

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NeilMed Sinus Rinse Refill Packets, 100 Count (Packaging May Vary)

NeilMed Sinus Rinse Refill Packets, 100 Count (Packaging May Vary)

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Boiron Sinusalia, 60 Tablets, Homeopathic Medicine for Nasal Congestion and Pain Related to Sinus Inflammation Like Stuffy Nose and Sinus Pressure, Non-Drowsy, For Ages 4 to Adult

Boiron Sinusalia, 60 Tablets, Homeopathic Medicine for Nasal Congestion and Pain Related to Sinus Inflammation Like Stuffy Nose and Sinus Pressure, Non-Drowsy, For Ages 4 to Adult

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Reactine Extra Strength Antihistamine Liquid Gel Pills - 10mg Cetirizine Hydrochloride - Allergy Relief Medicine - 25 count

Reactine Extra Strength Antihistamine Liquid Gel Pills - 10mg Cetirizine Hydrochloride - Allergy Relief Medicine - 25 count

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6

TYLENOL Extra Strength Sinus eZ Tabs, Relieves Sinus congestion and other sinus Symptoms, Daytime, 40ct
TYLENOL Extra Strength Sinus eZ Tabs, Relieves Sinus congestion and other sinus Symptoms, Daytime, 40ct

Tylenol

8.5

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7

TYLENOL Sinus Extra Strength eZ Tabs, Relieves Sinus congestion and other Sinus symptoms, Daytime and Nighttime, Convenience Pack, 40ct
TYLENOL Sinus Extra Strength eZ Tabs, Relieves Sinus congestion and other Sinus symptoms, Daytime and Nighttime, Convenience Pack, 40ct

Tylenol

8.2

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8

Otrivin Nasal Spray, Cold & Allergy Medication, Nasal Decongestant, Original Formula, 30 mL
Otrivin Nasal Spray, Cold & Allergy Medication, Nasal Decongestant, Original Formula, 30 mL

Zynxel

7.9

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9

Otrivin Nasal Spray, Cold & Allergy Medication with Moisturizer, Nasal Decongestant, 30 mL
Otrivin Nasal Spray, Cold & Allergy Medication with Moisturizer, Nasal Decongestant, 30 mL

Otrivin

7.6

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10

Drixoral Decongestant Nasal Spray, Fast and Long Lasting 12 Hour Relief, 30ml
Drixoral Decongestant Nasal Spray, Fast and Long Lasting 12 Hour Relief, 30ml

Drixoral

7.3

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