10 bestLaxatives For Severe Constipationof July 2025
112M consumers helped this year.
1

RestoraLAX Powder Stool Softener Laxative - Laxatives For Constipation, Effective Constipation Relief For Adults, No Taste, No Grit, No Gas, No Bloat, No Cramps, No Sudden Urge, 45 Doses, 765 grams
RestoraLAX

9.7
2

Lax-A-DAY Lax-A-Senna Sennosides Stimulant Laxative | Naturally Sourced Medicinal Ingredients, Fast-Acting, Overnight Relief of Occasionnal Constipation | 110 Tablets
LAX-A-DAY

9.4
3

Colace Glycerin Suppositories - Adult | Gentle Fast Acting Relief of Occasional Constipation | 48 Count
Colace

9.2
4

LAX-A-DAY Powder Laxative - No Taste, No Grit, No Sugar - Clinically Proven Relief of Occasional Constipation - Stimulates Bowel Movements - (7 Doses, 119 g)
LAX-A-DAY

8.9
5

RestoraLAX Powder Stool Softener Laxative - Laxatives For Constipation, Effective Constipation Relief For Adults, No Taste, No Grit, No Gas, No Bloat, No Cramps, No Sudden Urge, 14 Doses, 238 Grams
RestoraLAX

8.6
OtherUp to 5% off
6

RestoraLAX Powder Laxative, Effective Relief, No Taste, No Grit, No Gas, No Bloating, No Cramps, No Sudden Urge, Convenient 10 Single Dose Sachets
RestoraLAX

8.3
7

Colace Glycerin Suppositories - Adult | Gentle Fast Acting Relief of Occasional Constipation | 24 Count
FUAUFAS

8.1
8

Dulcolax Soft Chews, Mixed Berry, Dependable and Gentle, Laxatives for Fast Occasional Constipation Relief, Vegan, Stimulant-Free, Gluten-Free, For Adults & Kids Ages 12 and Over, 30 Count
Dulcolax

7.8
9

Senokot Natural Senna Laxative Plus Stool Softener, 60 Count
Senokot

7.5
10

RestoraLAX Powder Laxative, Effective Relief, No Taste, No Grit, No Gas, No Bloating, No Cramps, No Sudden Urge, 30 Doses, 510 grams
RestoraLAX

7.2
A Guide to Selecting the Best Laxatives For Severe Constipation
Choosing the right laxative for severe constipation can make a big difference in your comfort and health. It's important to understand that not all laxatives work the same way, and some are better suited for certain situations or people. Before picking a product, think about your symptoms, how quickly you need relief, and any health conditions you may have. Always consider talking to a healthcare professional before starting a new laxative, especially for severe or ongoing constipation.
Type of Laxative
Laxatives come in several types, including bulk-forming, stimulant, osmotic, stool softeners, and lubricants. Each type works differently: bulk-forming laxatives add fiber to your stool, stimulants trigger your intestines to move, osmotic laxatives draw water into the bowel, stool softeners moisten the stool, and lubricants coat the stool to help it pass. The type you choose should match your needs—if you want gentle, gradual relief, bulk-forming or stool softeners may be best, while stimulants or osmotics are often used for more immediate or severe cases. Your health history and how your body reacts to different types should guide your choice.
Onset of Action
This refers to how quickly the laxative starts working. Some laxatives work within a few hours, while others may take a day or more. Fast-acting options are helpful if you need quick relief, but they may also cause more cramping or urgency. Slower-acting laxatives are gentler and better for regular use or prevention. Think about how urgently you need relief and whether you can wait for a slower, milder effect.
Formulation
Laxatives are available in many forms, such as tablets, capsules, powders, liquids, and suppositories. The best form for you depends on your preferences and any swallowing difficulties or sensitivities you may have. For example, suppositories or enemas act locally and quickly, while oral forms are more convenient for regular use. Choose a formulation that fits your comfort and lifestyle.
Potential Side Effects
Different laxatives can cause different side effects, such as cramping, bloating, diarrhea, or dehydration. Some types, especially stimulants, are more likely to cause discomfort or dependency if used too often. If you have sensitive digestion or other health concerns, look for options with fewer side effects and always follow the recommended usage instructions.
Suitability for Long-Term Use
Some laxatives are safe for occasional use, while others can be used regularly. Bulk-forming and some stool softeners are generally safe for longer periods, but stimulant and certain osmotic laxatives should not be used continuously without medical advice. If you expect to need ongoing help with constipation, choose a product that is safe for long-term use and check with your doctor.

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