10 bestFresh Cold Sore Treatmentsof December 2025
112M consumers helped this year.
30% off
1

Abreva Cream Tube Cold Sore Treatment, Heals your cold sore in 4.1 days*, Contains docosanol to protect healthy cells against the virus, 2 g
Abreva

9.9
2

Red Light Therapy Device, Cold Sore Canker Sore T.re.atment for Lips, In.frared Light Therapy for Mouth Nose Ear Knee Feet Hands Joint P.a.i.n Relief
KTS

9.8
3

Mederma Discreet Cold Sore Healing Patch - Twin Pack to Protect and Conceal Cold Sores (30 Patches)
Mederma

9.6
10% off
4

Listerine Fresh Burst Antiseptic Mouthwash, Essential Oils Menthol, Thymol, Eucalpytol, Plaque, Bad Breath, Gingivitis, 1.5L
Listerine

9.4
5

Organika Bee Propolis Liquid- Natural Immune Support, Sore Throat Relief, Antioxidant, Alcohol-Free- 30 ml
Organika

9.2
OtherUp to 35% off
6

DocoShield Cold Sore Prevention Lip Balm w/Docosanol and Lysine (3-Pack)
DOCO

8.9
7

Compeed Cold Sore Patch - 15 Pack - Pack of 2
Compeed

8.6
8

A.Vogel Echinaforce Sore Throat Spray Fast Acting Relief | Antibacterial | Clinically Proven | Fast-Acting Treatment for Pharyngitis, Tonsillitis, Soreness and Hoarseness | Organically Grown Echinacea Purpurea Herb Tincture | Vegan and Cruelty-Free | 30mL
A.Vogel

8.4
9

Dynamiclear Rapid Cold Sore Treatment, One-and-Done, All-Natural Single Application Topical One Dose Cold Sore Medication | Two applications per box | Licensed under NPN 80086208
Dynamiclear Rapid

8.1
10

Abreva Only FDA Approved Cold Sore Treatment/Fever Blister Medicine to Shorten the Duration of Healing Time, Docosanol 10% Cream, Tube, 0.07 Ounces
Abreva

7.8
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