10 bestEnzyme Cleaner For Dog Urineof December 2025
112M consumers helped this year.
1

Simple Solution Pet Stain and Odor Remover | Enzymatic Cleaner with 2X Pro-Bacteria Cleaning Power | Floral Fresh, 1 Gallon
Simple Solution

9.7
2

Nature’s Miracle Advanced Stain and Odor Eliminator Dog, 32 Ounces, Spray, Fresh Scent, Severe Mess Enzymatic Formula For Tough Pet Messes
Nature's Miracle

9.4
5% off
3

ez-clean Advanced Odor Remover- Highly Concentrated Bio Enzyme Pet Odor Eliminator for Dog, Cat, and Small Animal Urine Indoor & Outdoor Use for Any Organic Spills(1 L (Pack of 1))
ez-clean

9.1
14% off
4

Nature's Miracle® Urine Destroyer Plus Dog 32 fl oz RTU
Nature's Miracle

8.8
5

Professional Strength Stain & Odor Eliminator - Enzyme-Powered Pet Odor & Stain Remover for Dogs and Cat Urine - Spot Carpet Cleaner - Small Animal Odor Remover (32 oz)
Rocco & Roxie Supply Co

8.5
Other
6

Ur-in Control Enzyme Pet Cleaner - Removes Dog & Cat Urine Odors & Stains on Carpet, Furniture, Tile & More - Pet & Human Safe Biodegradable Enzymes for Destroying Odors
Black Diamond Stoneworks

8.2
5% off
7

Outdoor Odor Eliminator | Outside Dog Urine Enzyme Cleaner – Powerful Pet, Cat, Animal Scent Deodorizer | Professional Strength for Yard, Turf, Kennels, Patios, Decks (32oz)
Eco Strong

7.9
8

Simple Solution Extreme Urine Destroyer Enzymatic Cleaner | Pet Stain and Odor Remover with 2X Pro-Bacteria Cleaning Power | 32 Ounces
Simple Solution

7.6
5% off
9

ez-clean Advanced Yard Odor Remover- Highly Concentrated Bio Enzyme - Pet Odor Eliminator for Dog Urine -Outdoor Use with Hoser attachement (1 L Spray with Hose Attachment)
ez-clean

7.3
14% off
10

Angry Orange - Best Enzyme Pet Odor Eliminator And Stain Remover To Destroy Cat And Dog Urine 32oz Spray Bottle -Fresh Non Citrus Scent
ANGRY ORANGE

7.0
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