10 bestDry Mouth Medicationof January 2026
112M consumers helped this year.
1
XyliMelts - Dry Mouth Product made with Xylitol - Stimulates Saliva Production Naturally - Mint Free - Value Pack of 4 x 40-Count Boxes - Sticky Time-Release Xylitol Lozenges - Canadian Version
OraCoat
9.7
2
Biotene Dry Mouth Lozenges, Refreshing Mint, 81 Count
biotène
9.4
7% off
3
biotène Dry Mouth Moisturizing Spray, 44ml
biotène
9.2
4
Oracoat XyliMelts Dry Mouth Relief Moisturizing Stick-On Melts Berry Smoothie with Xylitol, for Dry Mouth, Stimulates Saliva, Non-Acidic, Day and Night Use, Time Release for up to 8 Hours, 100 Count
OraCoat
8.9
5% off
5
Biotene Dry Mouth Moisturizing Mouthwash Fresh Mint, 473ml
biotène
8.6
OtherUp to 43% off
TheraBreath Dry Mouth Lozenges with Added ZINC - Mandarin Mint | Supports & Enhances Your Natural Saliva Production | 72 Count
Nature's Stance XyliDENT Xylitol Tablets for Dry Mouth Relief - Stimulates Saliva, Freshens Breath, Reduces Acid Production, Fast Acting Relief, 100 Count (Wintergreen)
Cotton Mouth Dry Mouth Lozenges Fruit Mix Bag
TheraBreath Dry Mouth Lozenges, Tart Berry Flavor, 24 Lozenges
5% off
6
Allday Dry Mouth Spray - Maximum Strength Xylitol, Fast Acting, Long Lasting, Non-Acidic (Pack of 2)
Allday
8.3
5% off
7
biotène Dry Mouth oralbalance Moisturizing Gel, 42g
biotène
8.1
8
OraCoat XyliMelts Dry Mouth Relief Oral Adhering Discs Slightly Sweet with Xylitol, For Dry Mouth, Stimulates Saliva, Non-Acidic, Day and Night Use, Time Release for up to 8 Hours, 100 Count.
OraCoat
7.8
9
OASIS DRY MOUTH SPRAY 1 OZ 6 Pack
OASIS
7.5
10
Biotène Dry Mouth Management Rinse, Spray, Gel Kit
biotène
7.2
A Guide to Selecting the Best Dry Mouth Medication
Choosing the right medication for dry mouth (also known as xerostomia) can make a big difference in your comfort and oral health. The best approach is to understand what causes your dry mouth—whether it's a side effect of another medication, a medical condition, or something else—and then look for a product that addresses your specific needs. It's important to know that dry mouth medications come in various forms, such as lozenges, sprays, gels, and rinses, and each has its own advantages. Always consult with a healthcare professional before starting any new medication, especially if you have other health conditions or are taking other drugs.
Active Ingredients
Active ingredients are the main components in a medication that help relieve dry mouth symptoms. Some products use ingredients that stimulate saliva production, while others simply provide moisture. For example, xylitol is often used to help stimulate saliva, while glycerin or carboxymethylcellulose are used to coat and moisten the mouth. If your dry mouth is mild, a moisturizing agent may be enough, but if you need more stimulation, look for products with saliva-stimulating ingredients. Always check for any allergies or sensitivities to these ingredients.
Form of Medication
Dry mouth medications come in several forms, including lozenges, sprays, gels, rinses, and chewing gum. Lozenges and chewing gum are good for on-the-go relief and can help stimulate saliva. Sprays and gels are more targeted and can provide longer-lasting moisture, which is helpful at night or for severe dryness. Rinses are easy to use and can cover the whole mouth quickly. Your choice should depend on when and where you need relief—if you need something discreet for work, lozenges or gum might be best, while gels or sprays are better for home use or overnight.
Duration of Relief
This refers to how long the medication keeps your mouth feeling moist and comfortable. Some products offer quick but short-term relief, while others are designed to last for several hours. If your dry mouth is persistent throughout the day or night, look for products that advertise long-lasting effects. If you only need occasional relief, a product with a shorter duration may be sufficient. Think about your daily routine and when your symptoms are worst to help guide your choice.
Flavor and Taste
Since dry mouth medications are often used multiple times a day, the flavor can make a big difference in your willingness to use them regularly. Some people prefer mild or unflavored options, especially if they are sensitive to strong tastes, while others enjoy minty or fruity flavors. If you have taste sensitivities or dislike certain flavors, check the product description before buying. Picking a flavor you enjoy can make it easier to stick with your treatment.
Sugar Content
Some dry mouth products contain sugar to improve taste, but sugar can increase the risk of tooth decay, especially when saliva is low. If you are concerned about dental health, look for sugar-free options, which are widely available and often use xylitol, a sweetener that is actually good for your teeth. This is especially important if you use the product frequently or overnight.
Alcohol Content
Alcohol is sometimes used in mouth rinses, but it can actually make dry mouth worse by drying out the tissues. If you have sensitive gums or severe dryness, it's best to choose alcohol-free products. Always check the label, especially if you have a history of mouth irritation or are using the product multiple times a day.
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