10 bestDrugstore Hand Creamsof December 2025
112M consumers helped this year.
1
Aveeno Hand Cream, Intense Relief for Dry and Cracked Skin, Unscented Moisturizer, 97 mL (Packaging May Vary)
Aveeno
10.0
2
O'Keeffe's Working Hands Hand Cream for Extremely Dry, Cracked Hands, Heals, Relieves and Repairs, Boosts Moisture Levels, 3.4oz/96g Jar, Moisturizer (Pack of 1) K1350013
O'Keeffe's
10.0
3
O'Keeffe's Working Hands Hand Cream for Extremely Dry, Cracked Hands, Heals, Relieves and Repairs, Boosts Moisture Levels, 3oz/85g, (Pack of 1) K1290003
O'Keeffe's
9.9
4
Glysomed Hand Cream 2 x 250 ML + 50 ML, 2 Count
Glysomed
9.7
5
Gold Bond Healing Hand Cream, 85ml Tube, 100% Non-Greasy Cream Formulated With 7 Intensive Moisturizers and 3 Skin-Nurturing Vitamins to Hydrate and Repair Dry Hands
Gold Bond
9.5
OtherUp to 13% off
Neutrogena Hydro Boost Hand Gel Cream, Hand Lotion Moisturizer with Hyaluronic Acid, 85g
Panier des Sens - Hand Cream for Dry Cracked Hands and Skin – Verbena Hand Lotion, Moisturizer, Mask - With Shea Butter and Olive Oil - Made in France 97% Natural Ingredients - 2.6floz/75ml
Hand Cream Gift Set - Spa Luxetique Hand Cream Set - 6x30ml Shea Butter Hand Moisturiser, Mini Hand Cream for Very Dry Hands with Vitamin E, Natural Aloe, Gift Sets for Women
Neutrogena Norwegian Formula Unscented Hand Cream, Dry Skin, Instantly Smoothing,Fragrance Free, 50mL
16% off
6
Glysomed Chamomile Hand Cream, 6.7 Fl Oz
Glysomed
9.4
7
EUCERIN Complete Repair Moisturizing Hand Cream for Dry Hands, 5% Urea Cream Hand Moisturizer + Ceramides, Fragrance-Free, Non-Greasy Dry Skin Cream, Dermatological Skin Care, 75mL
Eucerin
9.2
8
Hand Cream Gift Set - Pack of 12 Hand Lotion Enriched with Shea Butter and Glycerin to Nourish and Deeply Moisturize Rough Hands, 12 x 1.0 oz Travel Size Hand Lotion, Best Gifts for Women
BODY & EARTH
9.0
9
Eucerin Advanced Repair Hand Creme, 2.7 Ounce (Pack of 3)
Eucerin
8.8
10
Kiehl's Ultimate Strength Hand Salve, Deeply Hydrating Hand Lotion, Thick and Rich Formula for Intense Moisture and Conditioning, Protects and Repairs Dry Hands, Paraben and Gluten Free - 5 fl oz
Kiehl's
8.6
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