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10 bestDrugstore Hand Creamsof December 2025

112M consumers helped this year.

1

Aveeno Hand Cream, Intense Relief for Dry and Cracked Skin, Unscented Moisturizer, 97 mL (Packaging May Vary)
Aveeno Hand Cream, Intense Relief for Dry and Cracked Skin, Unscented Moisturizer, 97 mL (Packaging May Vary)

Aveeno

10.0

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2

O'Keeffe's Working Hands Hand Cream for Extremely Dry, Cracked Hands, Heals, Relieves and Repairs, Boosts Moisture Levels, 3.4oz/96g Jar, Moisturizer (Pack of 1) K1350013
O'Keeffe's Working Hands Hand Cream for Extremely Dry, Cracked Hands, Heals, Relieves and Repairs, Boosts Moisture Levels, 3.4oz/96g Jar, Moisturizer (Pack of 1) K1350013

O'Keeffe's

10.0

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3

O'Keeffe's Working Hands Hand Cream for Extremely Dry, Cracked Hands, Heals, Relieves and Repairs, Boosts Moisture Levels, 3oz/85g, (Pack of 1) K1290003
O'Keeffe's Working Hands Hand Cream for Extremely Dry, Cracked Hands, Heals, Relieves and Repairs, Boosts Moisture Levels, 3oz/85g, (Pack of 1) K1290003

O'Keeffe's

9.9

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4

Glysomed Hand Cream 2 x 250 ML + 50 ML, 2 Count
Glysomed Hand Cream 2 x 250 ML + 50 ML, 2 Count

Glysomed

9.7

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5

Gold Bond Healing Hand Cream, 85ml Tube, 100% Non-Greasy Cream Formulated With 7 Intensive Moisturizers and 3 Skin-Nurturing Vitamins to Hydrate and Repair Dry Hands
Gold Bond Healing Hand Cream, 85ml Tube, 100% Non-Greasy Cream Formulated With 7 Intensive Moisturizers and 3 Skin-Nurturing Vitamins to Hydrate and Repair Dry Hands

Gold Bond

9.5

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16% off

6

Glysomed Chamomile Hand Cream, 6.7 Fl Oz
Glysomed Chamomile Hand Cream, 6.7 Fl Oz

Glysomed

9.4

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7

EUCERIN Complete Repair Moisturizing Hand Cream for Dry Hands, 5% Urea Cream Hand Moisturizer + Ceramides, Fragrance-Free, Non-Greasy Dry Skin Cream, Dermatological Skin Care, 75mL
EUCERIN Complete Repair Moisturizing Hand Cream for Dry Hands, 5% Urea Cream Hand Moisturizer + Ceramides, Fragrance-Free, Non-Greasy Dry Skin Cream, Dermatological Skin Care, 75mL

Eucerin

9.2

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8

Hand Cream Gift Set - Pack of 12 Hand Lotion Enriched with Shea Butter and Glycerin to Nourish and Deeply Moisturize Rough Hands, 12 x 1.0 oz Travel Size Hand Lotion, Best Gifts for Women
Hand Cream Gift Set - Pack of 12 Hand Lotion Enriched with Shea Butter and Glycerin to Nourish and Deeply Moisturize Rough Hands, 12 x 1.0 oz Travel Size Hand Lotion, Best Gifts for Women

BODY & EARTH

9.0

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9

Eucerin Advanced Repair Hand Creme, 2.7 Ounce (Pack of 3)
Eucerin Advanced Repair Hand Creme, 2.7 Ounce (Pack of 3)

Eucerin

8.8

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10

Kiehl's Ultimate Strength Hand Salve, Deeply Hydrating Hand Lotion, Thick and Rich Formula for Intense Moisture and Conditioning, Protects and Repairs Dry Hands, Paraben and Gluten Free - 5 fl oz
Kiehl's Ultimate Strength Hand Salve, Deeply Hydrating Hand Lotion, Thick and Rich Formula for Intense Moisture and Conditioning, Protects and Repairs Dry Hands, Paraben and Gluten Free - 5 fl oz

Kiehl's

8.6

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