10 bestDog Urine Neutralizersof July 2025
112M consumers helped this year.
1

Nature’s Miracle Advanced Stain and Odor Eliminator Dog, 32 Ounces, Spray, Fresh Scent, Severe Mess Enzymatic Formula For Tough Pet Messes
Nature's Miracle

9.9
2

ez-clean Advanced Odor Remover- Highly Concentrated Bio Enzyme - Pet Odor Eliminator for Dog, Cat, and Small Animal Urine - Indoor & Outdoor Use for Any Organic Spills (4L jug)
ez-clean

9.8
3

ez-clean Advanced Odor Remover- Highly Concentrated Bio Enzyme Pet Odor Eliminator for Dog, Cat, and Small Animal Urine Indoor & Outdoor Use for Any Organic Spills(1 L (Pack of 1))
ez-clean

9.6
4

Eco Strong Outdoor Odor Eliminator Outside Dog Urine Enzyme Cleaner Powerful Pet, Cat, Animal Scent Deodorizer | Professional Strength for Yard, Turf, Kennels, Patios, Decks (128 OZ)
Eco Strong

9.4
5

Nature's Miracle JFC Advanced Stain & Odor Remover - 128oz Pour
Nature's Miracle

9.2
OtherUp to 18% off
6

Eco Strong Pet Stain and Odor Remover - Cat Urine Enzyme Cleaner Destroyer, Urine Destroyer for Dogs, Pet Urine Enzyme Cleaner - 32 OZ
Eco Strong

8.9
18% off
7

Nature's Miracle JFC Urine Destroyer Plus - 32oz Squeeze
Nature's Miracle

8.7
8

Simple Green Outdoor Odor Eliminator for Pets, Dogs, 1 Gallon Refill - Ideal for Artificial Lawns & Patio, Milky White
SIMPLE GREEN

8.4
9

Arm & Hammer Pet Stain & Odour Remover Spray with Oxiclean, 950ml
Arm & Hammer Deodorizer

8.1
10

Nature's Miracle® Urine Destroyer Plus Dog 32 fl oz RTU
Nature's Miracle

7.8
A Guide to Selecting the Best Dog Urine Neutralizers
Choosing the right dog urine neutralizer is important for keeping your home clean, odor-free, and safe for both pets and people. The best product for you will depend on where you plan to use it, the severity of the stains or odors, and any sensitivities in your household. Understanding the key features of these products will help you make a choice that fits your needs and keeps your living space fresh.
Type of Neutralizer
Dog urine neutralizers come in different forms, such as sprays, powders, and liquids. Sprays are convenient for spot cleaning and quick application, while powders are often used for carpets and larger areas. Liquids can be poured or used in carpet cleaners for deep cleaning. The right type depends on where you need to use it most—sprays for furniture and small spots, powders for carpets, and liquids for bigger or repeated messes.
Active Ingredients
The active ingredients in a neutralizer determine how well it breaks down urine and removes odors. Enzyme-based products use natural enzymes to break down urine at a molecular level, which is very effective for both stains and smells. Chemical-based neutralizers may work faster but can sometimes leave residues or have strong scents. If you have pets or children, enzyme-based or natural ingredient options are usually safer and gentler.
Surface Compatibility
Not all neutralizers are safe for every surface. Some are designed for carpets and fabrics, while others are safe for hardwood, tile, or outdoor use. Always check if the product is suitable for the surfaces you need to treat. If you have a mix of surfaces, look for a multi-surface formula. For delicate materials, choose a product specifically labeled as safe for those surfaces to avoid damage.
Odor Elimination vs. Masking
Some products truly neutralize and remove odors, while others just mask them with fragrances. True odor eliminators use enzymes or other agents to break down the source of the smell, making them more effective in the long run. If you want lasting results, look for products that claim to neutralize or eliminate odors, not just cover them up.
Safety and Sensitivity
If you have pets, children, or anyone with allergies in your home, it's important to choose a neutralizer that is non-toxic and free from harsh chemicals. Check for products labeled as pet-safe, child-safe, or hypoallergenic. This ensures that the product won't cause irritation or harm to your loved ones while still being effective.
Ease of Use
Some neutralizers require extra steps like scrubbing, rinsing, or waiting for a certain period before the area can be used again. Others are simple spray-and-leave formulas. Consider how much time and effort you want to spend on cleaning. If you prefer quick and easy solutions, look for products that require minimal steps and dry quickly.

Best Reviews Guide Newsletter
Get exclusive articles, recommendations, shopping tips, and sales alerts
Sign up for our newsletter to receive weekly recommendations about seasonal and trendy products
Thank you for subscribing!
By submitting your email address you agree to our Terms and Conditions and Privacy Policy