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10 bestDog Calming Treats For Large Dogsof December 2025

112M consumers helped this year.

1

CB2 Hemp Oil for Dogs [225,000mg / 240ml] Organic - Extra Strength for Pain/Arthritis/Inflammation/Separation Anxiety/Stress/Aggression/Barking. Advanced Hip and Joint Supplement
CB2 Hemp Oil for Dogs [225,000mg / 240ml] Organic - Extra Strength for Pain/Arthritis/Inflammation/Separation Anxiety/Stress/Aggression/Barking. Advanced Hip and Joint Supplement

CANNANDA

9.8

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2

Zoe Better Than Rawhide Twists for Dogs, Peanut Butter Flavor, 12 Pack (5.2 oz)
Zoe Better Than Rawhide Twists for Dogs, Peanut Butter Flavor, 12 Pack (5.2 oz)

Zoe

9.6

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3

Hemp Calming Chews for Dogs with Anxiety and Stress - Dog Calming Treats - Dog Anxiety Relief - Storms, Barking, Separation - Valerian Root - Hemp Oil - Made in USA - 120 Soft Chews - Chicken Flavor
Hemp Calming Chews for Dogs with Anxiety and Stress - Dog Calming Treats - Dog Anxiety Relief - Storms, Barking, Separation - Valerian Root - Hemp Oil - Made in USA - 120 Soft Chews - Chicken Flavor

Helopssa

9.4

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4

CB2 OIL FOR DOGS - Ultra Concentrated CB2 For Pain & Anxiety. Advanced Hip and Joint Medicine. More Effective Than Glucosamine and Hemp Oil For Dogs. Natural Anti-inflammatory. Improves Mobility. Relief from: Pain / Arthritis / Inflammation / Separation Anxiety / Stress / Aggression / Excessive Barking. Calming & Relaxing Effect. 100% Pure and Natural. Made in CANADA
CB2 OIL FOR DOGS - Ultra Concentrated CB2 For Pain & Anxiety. Advanced Hip and Joint Medicine. More Effective Than Glucosamine and Hemp Oil For Dogs. Natural Anti-inflammatory. Improves Mobility. Relief from: Pain / Arthritis / Inflammation / Separation Anxiety / Stress / Aggression / Excessive Barking. Calming & Relaxing Effect. 100% Pure and Natural. Made in CANADA

CANNANDA

9.1

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5

NaturVet Quiet Moments Calming Aid Dog Supplement, Helps Promote Relaxation, Reduce Stress, Storm Anxiety, Motion Sickness for Dogs (Quiet Moments Plus Hemp, 180 Soft Chews)
NaturVet Quiet Moments Calming Aid Dog Supplement, Helps Promote Relaxation, Reduce Stress, Storm Anxiety, Motion Sickness for Dogs (Quiet Moments Plus Hemp, 180 Soft Chews)

NaturVet

8.8

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Related productsUp to 9% off

ColEaze Dog Calming Chews, Dog Calming Treat, Natural Ingredients Calming Aid for Dogs, Relief Anxiety for Dogs, Chicken Flavor 120 Count

ColEaze Dog Calming Chews, Dog Calming Treat, Natural Ingredients Calming Aid for Dogs, Relief Anxiety for Dogs, Chicken Flavor 120 Count

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Open Farm Calming Chews, Dog Supplement, Dog Vitamins, Promote Calmness and Reduce Anxiousness Using Traceable and Vet-Approved Ingredients, 12.7 oz, 90 Count

Open Farm Calming Chews, Dog Supplement, Dog Vitamins, Promote Calmness and Reduce Anxiousness Using Traceable and Vet-Approved Ingredients, 12.7 oz, 90 Count

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Zoë Better Than Rawhide Peanut Butter Flavour Twists for Dogs, 1kg (2.2 lb.)

Zoë Better Than Rawhide Peanut Butter Flavour Twists for Dogs, 1kg (2.2 lb.)

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Dog Calcium Bones Wrapped with Chicken & Pet Natural Chew Treats - Grain Free Organic Meat & Human Grade Dried Snacks in Bulk - Best Twists for Small & Large Dogs (300 Gram)

Dog Calcium Bones Wrapped with Chicken & Pet Natural Chew Treats - Grain Free Organic Meat & Human Grade Dried Snacks in Bulk - Best Twists for Small & Large Dogs (300 Gram)

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6

Fera Pets Calming Goat Milk Cat & Dog Food Topper – Vet Created - Pet Anxiety, Stress & Hyperactivity - Ashwagandha Supplement with GABA-60 Servings
Fera Pets Calming Goat Milk Cat & Dog Food Topper – Vet Created - Pet Anxiety, Stress & Hyperactivity - Ashwagandha Supplement with GABA-60 Servings

Fera Pet Organics

8.6

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7

WEALLIN Hemp Oil for Dogs and Cats - Omega-3, 6, 9 Rich Organic Extract - Eases Pet Anxiety, Pain, Skin & Coat Health - Stress Relief, Hip & Joint Support - Calming Treats (2 Pack)
WEALLIN Hemp Oil for Dogs and Cats - Omega-3, 6, 9 Rich Organic Extract - Eases Pet Anxiety, Pain, Skin & Coat Health - Stress Relief, Hip & Joint Support - Calming Treats (2 Pack)

WEALLIN

8.3

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8

Hemp Calming Chews for Dogs Anxiety 150 pcs - Dog Anxiety Relief - Dog Calming Chews - Melatonin for Dogs - for Stress, Travel, Check-up, Barking or Grooming - Dog Calming Treats
Hemp Calming Chews for Dogs Anxiety 150 pcs - Dog Anxiety Relief - Dog Calming Chews - Melatonin for Dogs - for Stress, Travel, Check-up, Barking or Grooming - Dog Calming Treats

OKKÖBI

8.0

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9

VetriScience Laboratories Composure, Calming Support for Dogs, 120 Peanut Butter Flavored Bite-Sized Chews
VetriScience Laboratories Composure, Calming Support for Dogs, 120 Peanut Butter Flavored Bite-Sized Chews

Vetri-Science Laboratories

7.7

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10

True Leaf Calming Support Chew 600G
True Leaf Calming Support Chew 600G

true leaf

7.4

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