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10 bestCold Sore Medicinesof November 2025

112M consumers helped this year.

16% off

1

TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Daytime and Nighttime, Convenience Pack, 40ct
TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Daytime and Nighttime, Convenience Pack, 40ct

Tylenol

10.0

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30% off

2

Abreva Cream Tube Cold Sore Treatment, Heals your cold sore in 4.1 days*, Contains docosanol to protect healthy cells against the virus, 2 g
Abreva Cream Tube Cold Sore Treatment, Heals your cold sore in 4.1 days*, Contains docosanol to protect healthy cells against the virus, 2 g

Abreva

10.0

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3

Mederma Discreet Cold Sore Healing Patch - Twin Pack to Protect and Conceal Cold Sores (30 Patches)
Mederma Discreet Cold Sore Healing Patch - Twin Pack to Protect and Conceal Cold Sores (30 Patches)

Mederma

9.8

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24% off

4

BENYLIN Extra Strength Sore Throat and Cough Syrup, Relieves Sore Throat and Wet Cough, 250 mL
BENYLIN Extra Strength Sore Throat and Cough Syrup, Relieves Sore Throat and Wet Cough, 250 mL

BENYLIN

9.6

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10% off

5

Webber Naturals L-Lysine 1000 mg, 60 Tablets, Prevents Cold Sores, Vegan
Webber Naturals L-Lysine 1000 mg, 60 Tablets, Prevents Cold Sores, Vegan

Webber Naturals

9.4

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Related productsUp to 35% off

Abreva Only FDA Approved Cold Sore Treatment/Fever Blister Medicine to Shorten the Duration of Healing Time, Docosanol 10% Cream, Tube, 0.07 Ounces

Abreva Only FDA Approved Cold Sore Treatment/Fever Blister Medicine to Shorten the Duration of Healing Time, Docosanol 10% Cream, Tube, 0.07 Ounces

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DocoShield Cold Sore Prevention Lip Balm w/Docosanol (3-Pack)

DocoShield Cold Sore Prevention Lip Balm w/Docosanol (3-Pack)

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Herstat Cold Sore Treatment - Clinically Proven to Treat Cold Sores Fast, 2g cream

Herstat Cold Sore Treatment - Clinically Proven to Treat Cold Sores Fast, 2g cream

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Boiron Coryzalia for colds and cold symptoms, 60 Tablets. Chewable Tablets for nasal congestion, runny nose, rhinitis. Non-drowsy Cold Medicine

Boiron Coryzalia for colds and cold symptoms, 60 Tablets. Chewable Tablets for nasal congestion, runny nose, rhinitis. Non-drowsy Cold Medicine

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6

Vicks DayQuil COMPLETE Cold, Flu & Congestion Liquid Medicine, 236 mL
Vicks DayQuil COMPLETE Cold, Flu & Congestion Liquid Medicine, 236 mL

Vicks

9.1

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7

NeoCitran Cold & Sore Throat for Nighttime Relief, Lemon, 10 Count
NeoCitran Cold & Sore Throat for Nighttime Relief, Lemon, 10 Count

DOCLOGE

8.8

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8

Vicks DayQuil COMPLETE Cold and Flu LiquiCaps Medicine, Non-Drowsy Daytime Multi-Symptom Relief for Cough , Congestion, Fever, Sore Throat Pain, 24 Count
Vicks DayQuil COMPLETE Cold and Flu LiquiCaps Medicine, Non-Drowsy Daytime Multi-Symptom Relief for Cough , Congestion, Fever, Sore Throat Pain, 24 Count

Vicks

8.5

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9

Dynamiclear Rapid Cold Sore Treatment, One-and-Done, All-Natural Single Application Topical One Dose Cold Sore Medication | Two applications per box | Licensed under NPN 80086208
Dynamiclear Rapid Cold Sore Treatment, One-and-Done, All-Natural Single Application Topical One Dose Cold Sore Medication | Two applications per box | Licensed under NPN 80086208

Dynamiclear Rapid

8.3

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10

Pack of 2 x Quantum Lipclear Lysine and Cold Sore Treatment All Natural Ointment - 0.25 oz
Pack of 2 x Quantum Lipclear Lysine and Cold Sore Treatment All Natural Ointment - 0.25 oz

Quantum

8.0

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