10 bestantihistamineof December 2025
112M consumers helped this year.
5% off
1

Reactine Extra Strength Antihistamine Tablets - 10mg Cetirizine Hydrochloride - 24 Hour Allergy Relief Medicine - 10 Count
Reactine

9.8
2

Aerius Allergy Medicine, Fast Relief, 24-Hour, non-drowsy, 15 Symptoms 80 count
Aerius

9.6
3

Reactine Extra Strength Tablets
Reactine

9.4
25% off
4

Reactine Rapid Dissolve Antihistamine Tablets, Extra Strength, Allergy Relief, 48 Count
Reactine

9.1
13% off
5

Allegra 24 Hour Allergy Medication, Non Drowsy, Fast and Effective Multi-Symptom Allergy Relief Medicine for Sneezing, Watery Eyes and Itchy Throat, Fexofenadine Hydrochloride 120 mg, 30 Tablets
Allegra

8.9
OtherUp to 8% off
6

Aerius Fast & Effective, Non Drowsy, 24-Hour Allergy Relief
Aerius

8.7
7

Aerius Allergy Medicine, Fast Relief, 24-Hour, Non-Drowsy, 15 Symptoms, 50 Tablets
Aerius

8.4
5% off
8

Claritin Liquid Capsules Allergy Medicine, Fast-acting 24-hour Non-drowsy Relief 10 Mg 40 Count
Claritin

8.1
5% off
9

Allegra 12 Hour Allergy Medication, Non Drowsy, Fast, Multi-Symptom Allergy Relief Medicine for Sneezing, Runny Nose, Itchy/Watery Eyes, Throat or Palate, Fexofenadine Hydrochloride 60 mg, 36 Tablets
Allegra

7.8
10

Allegra Hives, 12-Hour Itchy Skin Relief Due to Hives, Allergic Skin Reactions, Non-Drowsy Allergy Medication, 60 mg Fexofenadine Hydrochloride Antihistamine, Adults and Kids, 12 and Older, 36 Tablets
Allegra

7.6
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