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10 best100 Pure Cold Sore Treatmentsof December 2025

112M consumers helped this year.

1

Handcraft Blends Tea Tree Essential Oil - Huge 118 ml - 100% Pure and Natural - Premium Grade with Glass Dropper

Handcraft Blends Tea Tree Essential Oil - Huge 118 ml - 100% Pure and Natural - Premium Grade with Glass Dropper

Handcraft Blends Tea Tree Essential Oil - Huge 118 ml - 100% Pure and Natural - Premium Grade with Glass Dropper

Handcraft Blends

9.8

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2

BEEKEEPER'S NATURALS Propolis Throat Spray - 85mg Bee Propolis Extract - Natural Immune Support, Sore Throat Relief & Antioxodant Support - Antioxidants, Keto, Paleo, Gluten-Free 1.06 oz (Pack of 2)

BEEKEEPER'S NATURALS Propolis Throat Spray - 85mg Bee Propolis Extract - Natural Immune Support, Sore Throat Relief & Antioxodant Support - Antioxidants, Keto, Paleo, Gluten-Free 1.06 oz (Pack of 2)

BEEKEEPER'S NATURALS Propolis Throat Spray - 85mg Bee Propolis Extract - Natural Immune Support, Sore Throat Relief & Antioxodant Support - Antioxidants, Keto, Paleo, Gluten-Free 1.06 oz (Pack of 2)

Beekeeper's Naturals

9.6

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3

Handcraft Blends Organic Castor Oil in Glass Bottle - 473 ml - 100% Pure and Natural - Premium Grade Carrier Oil, Hair and Body Oil - for Hair, Eyelashes & Eyebrows - Expeller-Pressed and Hexane-Free

Handcraft Blends Organic Castor Oil in Glass Bottle - 473 ml - 100% Pure and Natural - Premium Grade Carrier Oil, Hair and Body Oil - for Hair, Eyelashes & Eyebrows - Expeller-Pressed and Hexane-Free

Handcraft Blends Organic Castor Oil in Glass Bottle - 473 ml - 100% Pure and Natural - Premium Grade Carrier Oil, Hair and Body Oil - for Hair, Eyelashes & Eyebrows - Expeller-Pressed and Hexane-Free

Handcraft Blends

9.3

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30% off

4

Abreva Cream Tube Cold Sore Treatment, Heals your cold sore in 4.1 days*, Contains docosanol to protect healthy cells against the virus, 2 g

Abreva Cream Tube Cold Sore Treatment, Heals your cold sore in 4.1 days*, Contains docosanol to protect healthy cells against the virus, 2 g

Abreva Cream Tube Cold Sore Treatment, Heals your cold sore in 4.1 days*, Contains docosanol to protect healthy cells against the virus, 2 g

Abreva

9.0

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18% off

5

COLD-FX Extra Strength, Ginseng, Extract, Reduce Chance Cold and Flu, Support Immune System - 45 Vegan Capsules

COLD-FX Extra Strength, Ginseng, Extract, Reduce Chance Cold and Flu, Support Immune System - 45 Vegan Capsules

COLD-FX Extra Strength, Ginseng, Extract, Reduce Chance Cold and Flu, Support Immune System - 45 Vegan Capsules

Cold-FX

8.7

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OtherRelated productsUp to 11% off

Nature's Bounty L-Lysine Supplement, Helps Reduce the Recurrence of Herpes Simplex Virus, 1000mg, 60 Tablets

Nature's Bounty L-Lysine Supplement, Helps Reduce the Recurrence of Herpes Simplex Virus, 1000mg, 60 Tablets

Renew Actives Fast-Acting L-Lysine 1000mg with Zinc & Vitamin C – Maximum Strength Cold Sore Relief & Herpes Simplex Virus (HSV) – Promotes Healthy Collagen Production for Hair, Skin & Nails – Easy to Swallow, Vegan, Made in Canada.

Renew Actives Fast-Acting L-Lysine 1000mg with Zinc & Vitamin C – Maximum Strength Cold Sore Relief & Herpes Simplex Virus (HSV) – Promotes Healthy Collagen Production for Hair, Skin & Nails – Easy to Swallow, Vegan, Made in Canada.

Organika Bee Propolis Throat Spray- Alcohol Free, Soothing, Immune Support- 30ml

Organika Bee Propolis Throat Spray- Alcohol Free, Soothing, Immune Support- 30ml

Ecla Skin Care (8oz / 240 ml) Aloe Vera Spray Mist - 100% Pure Aloe Vera Gel for Face, Body, & Hair - After Sun Care Soothing, Moisturizing for Sunburn, Razor Bumps, Cold-Pressed Aloe Vera (Gel)

Ecla Skin Care (8oz / 240 ml) Aloe Vera Spray Mist - 100% Pure Aloe Vera Gel for Face, Body, & Hair - After Sun Care Soothing, Moisturizing for Sunburn, Razor Bumps, Cold-Pressed Aloe Vera (Gel)

6

MAJESTIC PURE Vitamin E Oil - 100% Pure & Natural, 20,000 IU | Premium Grade, Cold-Pressed and Tocopherol to Repair Dry, Damaged Skin| Moisturizing Skin, Hair and Scalp 8 Fl Oz

MAJESTIC PURE Vitamin E Oil - 100% Pure & Natural, 20,000 IU | Premium Grade, Cold-Pressed and Tocopherol to Repair Dry, Damaged Skin| Moisturizing Skin, Hair and Scalp 8 Fl Oz

MAJESTIC PURE Vitamin E Oil - 100% Pure & Natural, 20,000 IU | Premium Grade, Cold-Pressed and Tocopherol to Repair Dry, Damaged Skin| Moisturizing Skin, Hair and Scalp 8 Fl Oz

MAJESTIC PURE

8.4

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10% off

7

Webber Naturals L-Lysine 1000 mg, 60 Tablets, Prevents Cold Sores, Vegan

Webber Naturals L-Lysine 1000 mg, 60 Tablets, Prevents Cold Sores, Vegan

Webber Naturals L-Lysine 1000 mg, 60 Tablets, Prevents Cold Sores, Vegan

Webber Naturals

8.1

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8

Organika Bee Propolis Liquid- Natural Immune Support, Sore Throat Relief, Antioxidant, Alcohol-Free- 30 ml

Organika Bee Propolis Liquid- Natural Immune Support, Sore Throat Relief, Antioxidant, Alcohol-Free- 30 ml

Organika Bee Propolis Liquid- Natural Immune Support, Sore Throat Relief, Antioxidant, Alcohol-Free- 30 ml

Organika

7.8

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9

NOW - L-Lysine 500mg 250 Capsules

NOW - L-Lysine 500mg 250 Capsules

NOW - L-Lysine 500mg 250 Capsules

NOW

7.5

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5% off

10

Dynamiclear Rapid Cold Sore Treatment, One-and-Done, All-Natural Single Application Topical One Dose Cold Sore Medication | Easy to use 1x application per outbreak | Two applications per box | 2-pack contains 4 applications | Licensed under NPN 80086208 (2-Pack)

Dynamiclear Rapid Cold Sore Treatment, One-and-Done, All-Natural Single Application Topical One Dose Cold Sore Medication | Easy to use 1x application per outbreak | Two applications per box | 2-pack contains 4 applications | Licensed under NPN 80086208 (2-Pack)

Dynamiclear Rapid Cold Sore Treatment, One-and-Done, All-Natural Single Application Topical One Dose Cold Sore Medication | Easy to use 1x application per outbreak | Two applications per box | 2-pack contains 4 applications | Licensed under NPN 80086208 (2-Pack)

Dynamiclear Rapid

7.2

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